Quick answer: This post compares PRP and Hyaluronic Acid for Knee Osteoarthritis Treatment head-to-head — how each works, where the evidence is stronger, and how we choose for patients in Raleigh & Cary. At the 12-month mark, the patients who received PRP injections showed significantly better results than those who received HA. Treatment Options for Knee Osteoarthritis Many people suffer from knee osteoarthritis (KOA), which causes pain in the knee when the cartilage that ac